HelixLang Labs · Laboratory Features

Central Dogma

DNA → mRNA → protein, with coupled-dynamics time series

Input

DNA Sequence * Promoter Strength 0.8

Transcription/Translation Parameters

Parameters appear after running "Transcribe / Translate / Coupled".

mRNA Sequence

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Protein Sequence

—

mRNA / Protein Concentration Timeline

Evolution

Directed-evolution simulation, fitness tracking and dN/dS statistics

Input Parameters

Initial DNA Target DNA Generations 50 Population Size Mutation Rate 0.02

Fitness Evolution

Diversity

DNA Comparison (Initial → Final) & dN/dS Statistics

Population

Spatial population dynamics and signaling-molecule fields

Input Parameters

Initial Cells Simulation Generations Grid Size

Population Growth Curve

Statistics Panel

—

Spatial Distribution Heatmap (color=cell count)

Signaling Molecule Field

CRISPR Gene Editing

PAM search · sgRNA design · off-target prediction · editing

Input

DNA Sequence Cas Variant

Target Position New Sequence (HDR repair template, for editing only)

PAM Sites

Position	PAM	Strand	spacer

sgRNA Info

Click "Design Guide"

Off-Target Prediction

Position	Sequence	Mismatches	Score

Edit Result (original vs edited, diff highlighted)

Epigenetics

Methylation · histone modification · CpG islands

Input

DNA Sequence Cell Type

Methylation Map (red=methylated · green=unmethylated)

CpG Islands

Start	End	Length	GC%	O/E

Histone Modifications (chromatin bands)

3D Morphology

L-system 3D morphogenesis with rotatable projection

Input

Preset Iterations 4 Rotation Angle 25°

Axiom (used when preset=custom) Rules (used when preset=custom, e.g. F=FF+[+F-F-F]-[-F+F+F])

3D Visualization (drag the rotation slider to view)

Statistics

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DNA Storage

Text→oligo encoding · lifecycle simulation · density analysis

Input

Text Data Encoding Scheme

Redundancy 2

Oligo List

#	Sequence	GC%	Homopolymer

Storage Density Comparison

Cost / Durability

—

Lifecycle Simulation (integrity & error rate)

—

SynBio Designer

Expression cassette · vector · validation · GenBank export

Input

Protein Sequence Promoter Terminator

CAI Optimization Restriction Site Removal His-tag

Cassette Sequence (annotated)

—

Validation Report (radar)

Vector Map (circular plasmid)

GenBank Output

Click "Export GenBank"

Flux Balance Analysis (FBA)

E. coli core metabolic model · flux solving · subsystem analysis

Model Overview

Click "Load Model"

Objective Reaction Glucose Uptake Rate (mmol/gDW/h) 10.0

Subsystem Reaction Distribution

FBA Objective Value

—

Flux Distribution (Top 15 reactions)

Reaction	Name	Subsystem	Flux

Metabolic Analysis Report

Click "Metabolic Analysis"

Protein Structure Prediction

Secondary structure · transmembrane helices · intrinsically disordered regions

Input

Protein Sequence Secondary Structure Method

Secondary Structure (H=helix E=sheet T=turn '-'=none)

Click "Predict Secondary Structure"

Secondary Structure Segments

Type	Start	End	Length	Score

Transmembrane Helices

Click "Transmembrane Prediction"

Hydrophobicity (GRAVY)

—

Intrinsically Disordered Regions

Click "Disorder Prediction"

Multi-Species Comparison

Codon usage bias · tRNA abundance · cross-species comparison

Species Selection

Species A Species B Data Type

Supported Species

Click "List Species"

Species A · —

Codon	Amino Acid	‰	Score

Species B · —

Codon	Amino Acid	‰	Score

Codon Usage Comparison (Top 20)

Debugger

Bytecode disassembly · variable watch · call stack · breakpoints · step/continue

Source Editor

Breakpoint Offset (offset) Breakpoint Line (optional) Condition (optional, e.g. energy<50)

Bytecode Disassembly (current instruction highlighted)

Click "Start Debug Session"

Variable Watch

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Call Stack

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Breakpoint List

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Cell State

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