Term	Overlap	P-value	Adjusted P-value	Old P-value	Old Adjusted P-value	Odds Ratio	Combined Score	Genes
Kinase Activator Activity (GO:0019209)	5/44	1.2556687734961762E-4	0.021616068164801366	0	0	11.607856974829453	104.26957245554043	MOB3C;GPRC5A;RGCC;GPRC5C;MYD88
Dipeptidase Activity (GO:0016805)	3/10	1.5489629637483566E-4	0.021616068164801366	0	0	38.51298701298701	337.8649886229295	CPQ;DPEP2;PEPD
Complement Receptor Activity (GO:0004875)	3/11	2.11231936463857E-4	0.021616068164801366	0	0	33.69715909090909	285.16402182337157	C5AR2;FPR1;FPR2
Protein Kinase Activator Activity (GO:0030295)	6/88	4.5478610904248906E-4	0.03265170672831017	0	0	6.641002585141059	51.107052952423565	MOB3C;GPRC5A;RGCC;NRG1;GAS6;GPRC5C
NADP Binding (GO:0050661)	4/35	6.006017848427868E-4	0.03265170672831017	0	0	11.634114007954043	86.29695312516071	GRHPR;HMGCR;DHCR7;TM7SF2
3',5'-Cyclic-Nucleotide Phosphodiesterase Activity (GO:0004114)	3/16	6.879702574322844E-4	0.03265170672831017	0	0	20.731468531468533	150.96168094436462	PDE1C;PDE4B;PDE9A
Peptidase Inhibitor Activity (GO:0030414)	4/37	7.445014563458346E-4	0.03265170672831017	0	0	10.927909229279093	78.71149814978787	SLPI;PROS1;TIMP2;TIMP1
Cytokine Receptor Activity (GO:0004896)	5/76	0.0016010859992918148	0.05030594988329056	0	0	6.365809536115777	40.977181518336124	CD74;IL1R1;IFNLR1;IL12RB1;CRLF2
Endopeptidase Inhibitor Activity (GO:0004866)	6/112	0.001610077324694995	0.05030594988329056	0	0	5.131119033127554	33.00065389785822	SERPINB2;SLPI;PROS1;TIMP2;NRG1;TIMP1
Alpha-Mannosidase Activity (GO:0004559)	2/6	0.0018024933182937985	0.05030594988329056	0	0	44.73529411764706	282.6637313498237	MAN2A2;MAN2B1
Aminophospholipid Flippase Activity (GO:0015247)	2/6	0.0018024933182937985	0.05030594988329056	0	0	44.73529411764706	282.6637313498237	ATP8A1;ATP11C
Calmodulin-Dependent Protein Kinase Activity (GO:0004683)	3/23	0.002054123753480244	0.05255133269320291	0	0	13.470681818181818	83.35531175973883	CAMK1D;CAMK2A;PHKA2
3',5'-cyclic-GMP Phosphodiesterase Activity (GO:0047555)	2/7	0.0025049700930211793	0.054930415611250144	0	0	35.78642533936652	214.34202456901988	PDE1C;PDE9A
CD4 Receptor Binding (GO:0042609)	2/7	0.0025049700930211793	0.054930415611250144	0	0	35.78642533936652	214.34202456901988	CD74;PLSCR1
Type II Transforming Growth Factor Beta Receptor Binding (GO:0005114)	2/8	0.0033154681643717187	0.06361554540388235	0	0	29.82051282051282	170.24997279129462	TGFBR1;ENG
Mannosidase Activity (GO:0015923)	2/8	0.0033154681643717187	0.06361554540388235	0	0	29.82051282051282	170.24997279129462	MAN2A2;MAN2B1
Acylglycerol O-acyltransferase Activity (GO:0016411)	3/29	0.004035015549465593	0.07156562677510807	0	0	10.358916083916084	57.10606412760404	PLA2G15;DGAT1;GPAT3
Amino Acid:Monoatomic Cation Symporter Activity (GO:0005416)	2/9	0.004231513154383884	0.07156562677510807	0	0	25.559146735617325	139.6857370505713	SLC36A2;SLC6A13
Growth Factor Receptor Binding (GO:0070851)	5/96	0.004429143025169555	0.07156562677510807	0	0	4.961689686460328	26.890121180780156	PLSCR1;IL1R1;PDGFC;TLR9;IL12RB1
Glycerophospholipid Flippase Activity (GO:0140333)	2/10	0.005250671986481655	0.08059781499249341	0	0	22.3631221719457	117.39295593286606	ATP8A1;ATP11C
Protein Kinase Regulator Activity (GO:0019887)	5/103	0.005959593997315936	0.087123588436952	0	0	4.605645010297697	23.593581431806697	MOB3C;RGCC;CDKN1B;GPRC5A;GPRC5C
Platelet-Derived Growth Factor Receptor Binding (GO:0005161)	2/12	0.007588801788432651	0.10129400648038364	0	0	17.88868778280543	87.31614419757516	IL1R1;PDGFC
Potassium:Proton Antiporter Activity (GO:0015386)	2/12	0.007588801788432651	0.10129400648038364	0	0	17.88868778280543	87.31614419757516	SLC9A7;SLC9A9
3',5'-cyclic-AMP Phosphodiesterase Activity (GO:0004115)	2/13	0.008903107736292222	0.10512515673237355	0	0	16.261620732208968	76.77688239001534	PDE1C;PDE4B
NADPH Binding (GO:0070402)	2/13	0.008903107736292222	0.10512515673237355	0	0	16.261620732208968	76.77688239001534	GRHPR;HMGCR
Metalloendopeptidase Inhibitor Activity (GO:0008191)	2/13	0.008903107736292222	0.10512515673237355	0	0	16.261620732208968	76.77688239001534	TIMP2;TIMP1
Sodium:Proton Antiporter Activity (GO:0015385)	2/14	0.01031119631540333	0.11724212106773416	0	0	14.905731523378583	68.1866407995895	SLC9A7;SLC9A9
G Protein-Coupled Peptide Receptor Activity (GO:0008528)	4/77	0.01079805776485266	0.11839299049320594	0	0	4.930005629574029	22.32498325112933	VIPR1;FPR1;FPR2;GPR84
Sulfuric Ester Hydrolase Activity (GO:0008484)	2/15	0.011810832077153388	0.12042183471844146	0	0	13.758440654368256	61.07011604925034	IDS;SULF2
CoA Hydrolase Activity (GO:0016289)	2/15	0.011810832077153388	0.12042183471844146	0	0	13.758440654368256	61.07011604925034	ABCD2;ACOT11
Cell-Cell Adhesion Mediator Activity (GO:0098632)	3/43	0.012159859531829595	0.12042183471844146	0	0	6.728522727272727	29.670194437651755	CD47;S100A11;CD200
Transition Metal Ion Binding (GO:0046914)	11/456	0.013683772633189742	0.13127869369966408	0	0	2.254102183591266	9.673580115888754	PLA2G15;PLSCR1;NT5E;AGMO;QPCT;TIMP2;NRG1;TIMP1;MMP8;KLF4;JMJD6
Zinc Ion Binding (GO:0008270)	9/341	0.014631118426426353	0.1361137380882694	0	0	2.4631938970836615	10.406020316112665	PLA2G15;PLSCR1;NT5E;QPCT;TIMP2;NRG1;TIMP1;MMP8;KLF4
Solute:Potassium Antiporter Activity (GO:0022821)	2/17	0.015075991759366289	0.1361273373566309	0	0	11.922775263951735	50.011890127979775	SLC9A7;SLC9A9
Protein Homodimerization Activity (GO:0042803)	14/662	0.016818996541381782	0.13970351578340787	0	0	1.9774204028589994	8.078249354414622	ABCD2;TPI1;CPQ;CAMK2A;NAGA;GRHPR;NACC2;PDGFC;TLR9;PADI2;MVD;PDK2;S100A11;ABCG1
Transforming Growth Factor Beta Receptor Binding (GO:0005160)	2/18	0.016837231543928636	0.13970351578340787	0	0	11.177036199095022	45.648834132013505	TGFBR1;ENG
Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor (GO:0016628)	2/18	0.016837231543928636	0.13970351578340787	0	0	11.177036199095022	45.648834132013505	DHCR7;TM7SF2
Voltage-Gated Sodium Channel Activity (GO:0005248)	2/19	0.01868144913063386	0.14705653546422037	0	0	10.519031141868512	41.868103075141924	SCN3A;SCN1B
Cysteine-Type Endopeptidase Inhibitor Activity Involved In Apoptotic Process (GO:0043027)	2/19	0.01868144913063386	0.14705653546422037	0	0	10.519031141868512	41.868103075141924	TNFAIP8;GAS6
acyl-CoA Hydrolase Activity (GO:0047617)	2/20	0.020606592551555183	0.15815559783318603	0	0	9.93413775766717	38.565755552207406	ABCD2;ACOT11
Serine-Type Endopeptidase Inhibitor Activity (GO:0004867)	3/53	0.021289299016813493	0.15941011702833519	0	0	5.380090909090909	20.710932865497046	SERPINB2;SLPI;NRG1
Transforming Growth Factor Beta Binding (GO:0050431)	2/21	0.022610644922379686	0.16142948816675728	0	0	9.4108120981186	35.66071466780466	TGFBR1;ENG
Metal Cation:Proton Antiporter Activity (GO:0051139)	2/21	0.022610644922379686	0.16142948816675728	0	0	9.4108120981186	35.66071466780466	SLC9A7;SLC9A9
Iron Ion Binding (GO:0005506)	3/56	0.02459019033831424	0.17157246440596527	0	0	5.074785591766724	18.804149517796393	EGLN3;AGMO;JMJD6
Cytokine Receptor Binding (GO:0005126)	4/100	0.02571272092172065	0.17541789606596087	0	0	3.744482496194825	13.707687060890303	LIF;TLR9;TNFSF9;IL12RB1
Sterol Binding (GO:0032934)	3/59	0.028151163668318196	0.1826033869951247	0	0	4.802191558441558	17.144623846908825	INSIG1;PROM1;ABCG1
SH3 Domain Binding (GO:0017124)	3/59	0.028151163668318196	0.1826033869951247	0	0	4.802191558441558	17.144623846908825	PLSCR1;AFAP1;ESPN
Chemorepellent Activity (GO:0045499)	2/24	0.02907660215160496	0.1826033869951247	0	0	8.126285479226656	28.74934730476036	SEMA7A;NRG1
Carboxylic Ester Hydrolase Activity (GO:0052689)	4/104	0.029145166002479187	0.1826033869951247	0	0	3.593972602739726	12.706368702963601	PLA2G15;PGAP1;PNPLA7;DAGLB
Tumor Necrosis Factor Receptor Superfamily Binding (GO:0032813)	2/27	0.03618339167358877	0.22216602487583503	0	0	7.1500452488687785	23.732108859687578	TNFSF9;MYD88
Cell Adhesion Mediator Activity (GO:0098631)	2/28	0.038686172970379254	0.23287559023345944	0	0	6.8746954403063	22.358386572556473	CD47;CD200
Protein Tyrosine Kinase Activator Activity (GO:0030296)	2/29	0.04125292996949818	0.24355095193530657	0	0	6.619741913859561	21.103956594072937	NRG1;GAS6
O-acyltransferase Activity (GO:0008374)	2/31	0.04657150618321856	0.25577316797492256	0	0	6.162583866437822	18.899205016515968	PLA2G15;GPAT3
SH2 Domain Binding (GO:0042169)	2/31	0.04657150618321856	0.25577316797492256	0	0	6.162583866437822	18.899205016515968	TRPV4;AFAP1
Adenyl Nucleotide Binding (GO:0030554)	2/31	0.04657150618321856	0.25577316797492256	0	0	6.162583866437822	18.899205016515968	DHCR7;TM7SF2
Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling (GO:1903763)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	GJA5
Gap Junction Hemi-Channel Activity (GO:0055077)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	GJA5
CoA Carboxylase Activity (GO:0016421)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	PCCB
Intramolecular Oxidoreductase Activity, Interconverting Aldoses And Ketoses (GO:0016861)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	TPI1
N-acylsphingosine Amidohydrolase Activity (GO:0017040)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	NAAA
Acetylcholine Receptor Inhibitor Activity (GO:0030550)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	LY6E
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Another Compound As One Donor, And Incorporation Of One Atom Of Oxygen (GO:0016716)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	MSMO1
Amino Acid:Proton Symporter Activity (GO:0005280)	1/5	0.0545256459919934	0.25577316797492256	0	0	22.26689189189189	64.77626158965688	SLC36A2
MHC Protein Binding (GO:0042287)	2/34	0.05498706542783352	0.25577316797492256	0	0	5.583993212669683	16.19725065005577	CD74;MARCHF8
Nuclear Estrogen Receptor Binding (GO:0030331)	2/34	0.05498706542783352	0.25577316797492256	0	0	5.583993212669683	16.19725065005577	PADI2;TACC1
Sodium Ion Transmembrane Transporter Activity (GO:0015081)	2/34	0.05498706542783352	0.25577316797492256	0	0	5.583993212669683	16.19725065005577	SLC9A7;SLC9A9
Amyloid-Beta Binding (GO:0001540)	3/79	0.05837124543195249	0.26076575747141884	0	0	3.5348684210526318	10.042320400086451	CD74;RAMP3;FPR2
Sodium Channel Activity (GO:0005272)	2/37	0.06388948380858782	0.26076575747141884	0	0	5.1045895281189395	14.040686527622675	SCN3A;SCN1B
Galactosidase Activity (GO:0015925)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	NAGA
Gamma-Aminobutyric Acid Transmembrane Transporter Activity (GO:0015185)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	SLC6A13
Ubiquitin Ligase Activator Activity (GO:1990757)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	CDKN1B
MHC Class II Protein Binding (GO:0042289)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	CD74
RNA Polymerase III Type 3 Promoter Sequence-Specific DNA Binding (GO:0001006)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	ZFP36L1
Oxysterol Binding (GO:0008142)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	INSIG1
Peroxisome Proliferator Activated Receptor Binding (GO:0042975)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	TACC1
Ether Hydrolase Activity (GO:0016803)	1/6	0.0650702983365537	0.26076575747141884	0	0	17.81261261261261	48.66917131371123	EPHX1
Phosphatase Activity (GO:0016791)	3/83	0.06570454573961686	0.26076575747141884	0	0	3.357443181818182	9.14093171922342	DUSP5;NT5E;LPIN1
Sulfotransferase Activity (GO:0008146)	2/38	0.06695798043292593	0.26076575747141884	0	0	4.962543991955757	13.41718063535624	SULT1A1;CHST15
Fucose Binding (GO:0042806)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	CLEC10A
C-C Chemokine Binding (GO:0019957)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	CCR7
Unmethylated CpG Binding (GO:0045322)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	TLR9
L-proline Transmembrane Transporter Activity (GO:0015193)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	SLC36A2
RNA Polymerase III Cis-Regulatory Region Sequence-Specific DNA Binding (GO:0000992)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	ZFP36L1
Natural Killer Cell Lectin-Like Receptor Binding (GO:0046703)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	ULBP1
Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water (GO:0016717)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	FADS1
Peptidyl-Proline 4-Dioxygenase Activity (GO:0031545)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	EGLN3
Phosphatidylethanolamine Binding (GO:0008429)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	ESYT1
Sodium Channel Inhibitor Activity (GO:0019871)	1/7	0.0754978720995326	0.26076575747141884	0	0	14.843093093093094	38.349369451856326	SCN1B
2-Oxoglutarate-Dependent Dioxygenase Activity (GO:0016706)	2/41	0.07644598753233778	0.26076575747141884	0	0	4.580113702285648	11.776254762434943	EGLN3;JMJD6
Signal Sequence Binding (GO:0005048)	2/41	0.07644598753233778	0.26076575747141884	0	0	4.580113702285648	11.776254762434943	NFKBIA;CEMIP
Endopeptidase Regulator Activity (GO:0061135)	2/42	0.07969810947739951	0.268871644061117	0	0	4.4653846153846155	11.295232421530141	SLPI;PROS1
L-alanine Transmembrane Transporter Activity (GO:0015180)	1/8	0.08580966090141956	0.2729086287516557	0	0	12.722007722007723	31.240463430859748	SLC36A2
P-type Calcium Transporter Activity (GO:0005388)	1/8	0.08580966090141956	0.2729086287516557	0	0	12.722007722007723	31.240463430859748	ATP2B1
Nuclear Glucocorticoid Receptor Binding (GO:0035259)	1/8	0.08580966090141956	0.2729086287516557	0	0	12.722007722007723	31.240463430859748	TACC1
Activin Receptor Activity (GO:0017002)	1/8	0.08580966090141956	0.2729086287516557	0	0	12.722007722007723	31.240463430859748	TGFBR1
Cyclic-Nucleotide Phosphodiesterase Activity (GO:0004112)	1/8	0.08580966090141956	0.2729086287516557	0	0	12.722007722007723	31.240463430859748	PDE9A
Protein Serine/Threonine Kinase Activity (GO:0004674)	7/342	0.08920265171430786	0.2729086287516557	0	0	1.8807904919845218	4.5455781789610645	CAMK1D;CAMK2A;TESK1;PIM3;CAMK1;CDK14;TGFBR1
Superoxide-Generating NADPH Oxidase Activator Activity (GO:0016176)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	NCF4
Glycine Transmembrane Transporter Activity (GO:0015187)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	SLC36A2
Hydrolase Activity, Acting On Carbon-Nitrogen (But Not Peptide) Bonds, In Linear Amidines (GO:0016813)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	PADI2
Interleukin-1 Binding (GO:0019966)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	IL1R1
Interleukin-1 Receptor Binding (GO:0005149)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	TLR9
MAP Kinase Tyrosine Phosphatase Activity (GO:0033550)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	DUSP5
MAP Kinase Tyrosine/Serine/Threonine Phosphatase Activity (GO:0017017)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	DUSP5
Protein Binding Involved In Heterotypic Cell-Cell Adhesion (GO:0086080)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	CD47
Protein Tyrosine/Threonine Phosphatase Activity (GO:0008330)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	DUSP5
Cyclin-Dependent Protein Serine/Threonine Kinase Inhibitor Activity (GO:0004861)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	CDKN1B
siRNA Binding (GO:0035197)	1/9	0.09600694431654339	0.2729086287516557	0	0	11.131193693693694	26.084113030370332	TLR9
Transforming Growth Factor Beta Receptor Activity (GO:0005024)	1/10	0.10609098791758413	0.28850732806160745	0	0	9.893893893893894	22.196537153517223	TGFBR1
L-arginine Transmembrane Transporter Activity (GO:0061459)	1/10	0.10609098791758413	0.28850732806160745	0	0	9.893893893893894	22.196537153517223	SLC25A15
Nuclear Retinoid X Receptor Binding (GO:0046965)	1/10	0.10609098791758413	0.28850732806160745	0	0	9.893893893893894	22.196537153517223	TACC1
Semaphorin Receptor Activity (GO:0017154)	1/10	0.10609098791758413	0.28850732806160745	0	0	9.893893893893894	22.196537153517223	PLXNC1
Nuclear Receptor Coactivator Activity (GO:0030374)	2/50	0.10713301432906595	0.28850732806160745	0	0	3.7196455505279036	8.30851309405225	TACC1;TRERF1
Cholesterol Binding (GO:0015485)	2/50	0.10713301432906595	0.28850732806160745	0	0	3.7196455505279036	8.30851309405225	PROM1;ABCG1
Hexosaminidase Activity (GO:0015929)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	NAGA
P-type Ion Transporter Activity (GO:0015662)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	ATP2B1
Toll-like Receptor Binding (GO:0035325)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	MYD88
Organic Acid:Sodium Symporter Activity (GO:0005343)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	SLC6A13
cAMP Binding (GO:0030552)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	PDE4B
Phospholipid Scramblase Activity (GO:0017128)	1/11	0.11606304344778152	0.2969279528205744	0	0	8.904054054054054	19.175964540841118	PLSCR1
5'-Nucleotidase Activity (GO:0008253)	1/12	0.1259243488966605	0.30767665700623154	0	0	8.094185094185095	16.77175014431259	NT5E
Transmembrane Receptor Protein Tyrosine Kinase Activator Activity (GO:0030297)	1/12	0.1259243488966605	0.30767665700623154	0	0	8.094185094185095	16.77175014431259	NRG1
Monocarboxylate:Sodium Symporter Activity (GO:0140161)	1/12	0.1259243488966605	0.30767665700623154	0	0	8.094185094185095	16.77175014431259	SLC6A13
Amino Acid Transmembrane Transporter Activity (GO:0015171)	2/56	0.12910532945417716	0.30767665700623154	0	0	3.3053460700519524	6.76646219401455	SLC36A2;SLC6A13
Adenyl Ribonucleotide Binding (GO:0032559)	6/309	0.13254242426349236	0.30767665700623154	0	0	1.7770680293835834	3.5911923728404087	PDE4B;HMGCR;PDK2;SYN1;ABCG1;TGFBR1
Metalloexopeptidase Activity (GO:0008235)	2/57	0.13286376843489775	0.30767665700623154	0	0	3.2450843274372687	6.549978717124253	CPQ;PEPD
Insulin-Like Growth Factor Receptor Binding (GO:0005159)	1/13	0.1356761286696523	0.30767665700623154	0	0	7.4192942942942945	14.819926393575223	IGF1
I-SMAD Binding (GO:0070411)	1/13	0.1356761286696523	0.30767665700623154	0	0	7.4192942942942945	14.819926393575223	TGFBR1
Oxidoreductase Activity, Acting On The CH-NH Group Of Donors, NAD Or NADP As Acceptor (GO:0016646)	1/13	0.1356761286696523	0.30767665700623154	0	0	7.4192942942942945	14.819926393575223	ALDH1L1
Arylsulfatase Activity (GO:0004065)	1/13	0.1356761286696523	0.30767665700623154	0	0	7.4192942942942945	14.819926393575223	SULF2
Sodium:Chloride Symporter Activity (GO:0015378)	1/13	0.1356761286696523	0.30767665700623154	0	0	7.4192942942942945	14.819926393575223	SLC6A13
Nuclease Activity (GO:0004518)	2/58	0.13664692931667805	0.30767665700623154	0	0	3.186974789915966	6.343210691742598	PLSCR1;RNASE6
Nuclear Receptor Binding (GO:0016922)	3/115	0.13741475950022022	0.30767665700623154	0	0	2.3942775974025974	4.752046016994009	PADI2;TACC1;TRERF1
Carboxylic Acid Transmembrane Transporter Activity (GO:0046943)	2/59	0.14045380049373354	0.30767665700623154	0	0	3.1309041835357623	6.145578766567807	SLC36A2;SLC6A13
Receptor Tyrosine Kinase Binding (GO:0030971)	2/59	0.14045380049373354	0.30767665700623154	0	0	3.1309041835357623	6.145578766567807	NRG1;GAS6
1-Phosphatidylinositol-3-Kinase Regulator Activity (GO:0046935)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	SOCS6
Hyaluronic Acid Binding (GO:0005540)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	CEMIP
MAP Kinase Phosphatase Activity (GO:0033549)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	DUSP5
Acetylcholine Receptor Regulator Activity (GO:0030548)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	LY6E
Nucleotidase Activity (GO:0008252)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	NT5E
Acylglycerol Lipase Activity (GO:0047372)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	DAGLB
Alanine Transmembrane Transporter Activity (GO:0022858)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	SLC36A2
Aldehyde Dehydrogenase (NAD+) Activity (GO:0004029)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	ALDH1L1
Aldehyde Dehydrogenase [NAD(P)+] Activity (GO:0004030)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	ALDH1L1
Phospholipase A1 Activity (GO:0008970)	1/14	0.14531959370001163	0.30767665700623154	0	0	6.848232848232848	13.209007575154516	PLA2G15
Receptor Ligand Activity (GO:0048018)	6/319	0.14730175552896158	0.30935417619945765	0	0	1.719409313761576	3.293136579721759	SEMA7A;LIF;NRG1;IGF1;TIMP1;GAS6
G Protein-Coupled Receptor Activity (GO:0004930)	5/250	0.14812724397824195	0.30935417619945765	0	0	1.8284965362291705	3.491849880783352	VIPR1;C5AR2;FPR1;CCR7;FPR2
BMP Binding (GO:0036122)	1/15	0.15485594168828426	0.3169384939886885	0	0	6.358751608751609	11.860725042866767	ENG
Transmembrane Receptor Protein Serine/Threonine Kinase Activity (GO:0004675)	1/15	0.15485594168828426	0.3169384939886885	0	0	6.358751608751609	11.860725042866767	TGFBR1
Death Receptor Binding (GO:0005123)	1/15	0.15485594168828426	0.3169384939886885	0	0	6.358751608751609	11.860725042866767	MYD88
L-amino Acid Transmembrane Transporter Activity (GO:0015179)	2/63	0.1558988253528424	0.3169598634657127	0	0	2.9250055633855054	5.436263349700195	SLC25A15;SLC36A2
Protease Binding (GO:0002020)	3/125	0.16369948621106262	0.32964648110131684	0	0	2.196907600596125	3.9757940669436795	VWF;TIMP2;TIMP1
Ubiquitin-Protein Transferase Activator Activity (GO:0097027)	1/16	0.16428635703094943	0.32964648110131684	0	0	5.934534534534534	10.718625689027228	CDKN1B
Nuclear Retinoic Acid Receptor Binding (GO:0042974)	1/17	0.17361201123765793	0.3373347306959556	0	0	5.563344594594595	9.741039691029968	TACC1
Phosphatidylcholine Transporter Activity (GO:0008525)	1/17	0.17361201123765793	0.3373347306959556	0	0	5.563344594594595	9.741039691029968	ABCG1
Phosphatidylinositol 3-Kinase Regulator Activity (GO:0035014)	1/17	0.17361201123765793	0.3373347306959556	0	0	5.563344594594595	9.741039691029968	SOCS6
Basic Amino Acid Transmembrane Transporter Activity (GO:0015174)	1/17	0.17361201123765793	0.3373347306959556	0	0	5.563344594594595	9.741039691029968	SLC25A15
Cadherin Binding Involved In Cell-Cell Adhesion (GO:0098641)	1/17	0.17361201123765793	0.3373347306959556	0	0	5.563344594594595	9.741039691029968	S100A11
Calcium Ion Transmembrane Transporter Activity (GO:0015085)	2/68	0.17562500877736345	0.3390998597147835	0	0	2.7027286439051146	4.701137524712514	TRPV4;ATP2B1
Glutamate Receptor Binding (GO:0035254)	1/18	0.18283406284713427	0.34373455892429317	0	0	5.2358240593534715	8.89658814160068	CAMK2A
Mannose Binding (GO:0005537)	1/18	0.18283406284713427	0.34373455892429317	0	0	5.2358240593534715	8.89658814160068	CLEC10A
Amino Acid:Sodium Symporter Activity (GO:0005283)	1/18	0.18283406284713427	0.34373455892429317	0	0	5.2358240593534715	8.89658814160068	SLC6A13
Cholesterol Transfer Activity (GO:0120020)	1/18	0.18283406284713427	0.34373455892429317	0	0	5.2358240593534715	8.89658814160068	ABCG1
RNA Nuclease Activity (GO:0004540)	2/70	0.18362367317128364	0.34373455892429317	0	0	2.622970455150386	4.445585726121526	NYNRIN;RNASE6
Guanyl-Nucleotide Exchange Factor Activity (GO:0005085)	4/203	0.1916563537859181	0.3486968810283647	0	0	1.7969298547532182	2.9686203647902603	TIAM2;SPATA13;WDR41;ARHGEF40
1-Acylglycerol-3-Phosphate O-acyltransferase Activity (GO:0003841)	1/19	0.19195365763450697	0.3486968810283647	0	0	4.944694694694695	8.161225034428677	GPAT3
Sterol Transfer Activity (GO:0120015)	1/19	0.19195365763450697	0.3486968810283647	0	0	4.944694694694695	8.161225034428677	ABCG1
R-SMAD Binding (GO:0070412)	1/19	0.19195365763450697	0.3486968810283647	0	0	4.944694694694695	8.161225034428677	RGCC
Chemokine Receptor Activity (GO:0004950)	1/19	0.19195365763450697	0.3486968810283647	0	0	4.944694694694695	8.161225034428677	CCR7
Hormone Activity (GO:0005179)	2/74	0.1997707662092083	0.3545884031113505	0	0	2.4767471091000504	3.9890110956399947	CALCB;IGF1
Gap Junction Channel Activity (GO:0005243)	1/20	0.20097192879926704	0.3545884031113505	0	0	4.684210526315789	7.516237548253504	GJA5
Lysophosphatidic Acid Acyltransferase Activity (GO:0042171)	1/20	0.20097192879926704	0.3545884031113505	0	0	4.684210526315789	7.516237548253504	GPAT3
Actinin Binding (GO:0042805)	1/20	0.20097192879926704	0.3545884031113505	0	0	4.684210526315789	7.516237548253504	PROM1
Solute:Proton Symporter Activity (GO:0015295)	1/20	0.20097192879926704	0.3545884031113505	0	0	4.684210526315789	7.516237548253504	SLC36A2
Triglyceride Lipase Activity (GO:0004806)	1/21	0.20988999711492223	0.36404649217107976	0	0	4.449774774774775	6.946862488778015	DAGLB
Lysophospholipase Activity (GO:0004622)	1/21	0.20988999711492223	0.36404649217107976	0	0	4.449774774774775	6.946862488778015	PNPLA7
Cyclic Nucleotide Binding (GO:0030551)	1/21	0.20988999711492223	0.36404649217107976	0	0	4.449774774774775	6.946862488778015	PDE4B
Phospholipase Activity (GO:0004620)	2/77	0.21198831565314935	0.3656202972220048	0	0	2.377315233785822	3.68774873309108	PLA2G15;PNPLA7
Semaphorin Receptor Binding (GO:0030215)	1/22	0.2187089709159452	0.37510421268824123	0	0	4.237666237666238	6.441309181477695	SEMA7A
High Voltage-Gated Calcium Channel Activity (GO:0008331)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	SCN3A
Zinc Ion Transmembrane Transporter Activity (GO:0005385)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	SLC39A11
mRNA 3'-UTR AU-rich Region Binding (GO:0035925)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	ZFP36L1
Phospholipid Transfer Activity (GO:0120014)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	ESYT1
Protein Tyrosine/Serine/Threonine Phosphatase Activity (GO:0008138)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	DUSP5
Cyclin-Dependent Protein Kinase Activity (GO:0097472)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	CDK14
Cyclin-Dependent Protein Serine/Threonine Kinase Activity (GO:0004693)	1/23	0.22742994642545422	0.37538168576674436	0	0	4.044840294840295	5.99005663950512	CDK14
Nuclear Localization Sequence Binding (GO:0008139)	1/24	0.23605400770201446	0.3855058613930363	0	0	3.8687818253035644	5.585339638462004	NFKBIA
FAD Binding (GO:0071949)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	SQLE
Wide Pore Channel Activity (GO:0022829)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	GJA5
MHC Class II Protein Complex Binding (GO:0023026)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	CD74
Phosphatidylinositol-3,4-Bisphosphate Binding (GO:0043325)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	ARAP3
Epidermal Growth Factor Receptor Binding (GO:0005154)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	PLSCR1
Ferrous Iron Binding (GO:0008198)	1/25	0.2445822269849536	0.3855058613930363	0	0	3.707394894894895	5.220767282198595	EGLN3
Growth Factor Activity (GO:0008083)	2/85	0.24486528655258005	0.3855058613930363	0	0	2.147304148721583	3.021358011859472	LIF;NRG1
Protein Tyrosine Kinase Binding (GO:1990782)	2/85	0.24486528655258005	0.3855058613930363	0	0	2.147304148721583	3.021358011859472	NRG1;GAS6
NF-kappaB Binding (GO:0051059)	1/26	0.2530156645623291	0.392302065760783	0	0	3.558918918918919	4.891036067861408	NFKBIA
Neuropeptide Activity (GO:0160041)	1/26	0.2530156645623291	0.392302065760783	0	0	3.558918918918919	4.891036067861408	CALCB
Neuropeptide Hormone Activity (GO:0005184)	1/26	0.2530156645623291	0.392302065760783	0	0	3.558918918918919	4.891036067861408	CALCB
ADP Binding (GO:0043531)	1/27	0.2613553692045386	0.39720840765244236	0	0	3.421864171864172	4.59171135050736	ABCG1
Nuclear Thyroid Hormone Receptor Binding (GO:0046966)	1/27	0.2613553692045386	0.39720840765244236	0	0	3.421864171864172	4.59171135050736	TACC1
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen (GO:0016709)	1/27	0.2613553692045386	0.39720840765244236	0	0	3.421864171864172	4.59171135050736	SQLE
Carboxy-Lyase Activity (GO:0016831)	1/27	0.2613553692045386	0.39720840765244236	0	0	3.421864171864172	4.59171135050736	MVD
Histone Demethylase Activity (GO:0032452)	1/29	0.27775771671143934	0.41595911722152135	0	0	3.177123552123552	4.069914548766424	JMJD6
Metal Ion Transmembrane Transporter Activity (GO:0046873)	1/29	0.27775771671143934	0.41595911722152135	0	0	3.177123552123552	4.069914548766424	ATP2B1
Metallocarboxypeptidase Activity (GO:0004181)	1/29	0.27775771671143934	0.41595911722152135	0	0	3.177123552123552	4.069914548766424	PEPD
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor (GO:0016616)	2/95	0.2861853047421178	0.42649945900888425	0	0	1.9154381355519876	2.3964348373384317	GRHPR;HMGCR
Phospholipase A2 Activity (GO:0004623)	1/31	0.2937974302833757	0.43572855602413685	0	0	2.965015015015015	3.631742409991077	PLA2G15
Monocarboxylic Acid Transmembrane Transporter Activity (GO:0008028)	1/32	0.30168380060386396	0.4410329846923154	0	0	2.86922406277245	3.438408761889013	SLC6A13
Beta-Tubulin Binding (GO:0048487)	1/32	0.30168380060386396	0.4410329846923154	0	0	2.86922406277245	3.438408761889013	TRPV4
Protein Serine/Threonine Kinase Inhibitor Activity (GO:0030291)	1/32	0.30168380060386396	0.4410329846923154	0	0	2.86922406277245	3.438408761889013	CDKN1B
Transition Metal Ion Transmembrane Transporter Activity (GO:0046915)	1/33	0.3094824919145318	0.45021079808437414	0	0	2.779420045045045	3.2598532432040734	SLC39A11
Metalloendopeptidase Activity (GO:0004222)	2/101	0.3108947530745515	0.45021079808437414	0	0	1.7988025046848577	2.101542474751824	ADAM22;MMP8
Transcription Coactivator Binding (GO:0001223)	1/34	0.31719447466919926	0.45082733205298225	0	0	2.695058695058695	3.094574757796007	TRERF1
Hsp70 Protein Binding (GO:0030544)	1/34	0.31719447466919926	0.45082733205298225	0	0	2.695058695058695	3.094574757796007	MVD
Kinase Inhibitor Activity (GO:0019210)	1/34	0.31719447466919926	0.45082733205298225	0	0	2.695058695058695	3.094574757796007	CDKN1B
Sodium Channel Regulator Activity (GO:0017080)	1/34	0.31719447466919926	0.45082733205298225	0	0	2.695058695058695	3.094574757796007	SCN1B
Cytokine Activity (GO:0005125)	3/178	0.3191213638149241	0.4514758465031415	0	0	1.5274285714285714	1.7446041664601304	LIF;NRG1;TIMP1
Ion Channel Inhibitor Activity (GO:0008200)	1/35	0.324820708638239	0.457430997944676	0	0	2.6156597774244834	2.941262114472054	SCN1B
Phosphatidylinositol Binding (GO:0035091)	2/106	0.3313528080578446	0.46169763758688465	0	0	1.711886529759833	1.8909012190344223	MREG;ESYT1
Phosphatidylinositol-3,4,5-Trisphosphate Binding (GO:0005547)	1/36	0.3323621430185717	0.46169763758688465	0	0	2.540797940797941	2.7987654411162093	ARAP3
Protein Kinase C Binding (GO:0005080)	1/36	0.3323621430185717	0.46169763758688465	0	0	2.540797940797941	2.7987654411162093	TRPV4
GTPase Regulator Activity (GO:0030695)	6/424	0.33555205878519534	0.46402919841015755	0	0	1.2805547593323485	1.398337838637254	TIAM2;RGS2;SPATA13;WDR41;ARAP3;ARHGEF40
Monoatomic Cation Transmembrane Transporter Activity (GO:0008324)	1/37	0.3398197164973573	0.4657350578780745	0	0	2.470095095095095	2.6660725575111517	TRPV4
Monoatomic Ion Channel Activity (GO:0005216)	1/37	0.3398197164973573	0.4657350578780745	0	0	2.470095095095095	2.6660725575111517	TRPV4
Phosphatidylinositol Phosphate Binding (GO:1901981)	2/109	0.34354788566756644	0.4687520039997462	0	0	1.663635979193978	1.7774765461221957	NCF4;ARAP3
Alpha-Tubulin Binding (GO:0043014)	1/38	0.3471943574751525	0.4695536024003164	0	0	2.4032140248356466	2.542289337028832	TRPV4
Carboxypeptidase Activity (GO:0004180)	1/38	0.3471943574751525	0.4695536024003164	0	0	2.4032140248356466	2.542289337028832	PEPD
Pentosyltransferase Activity (GO:0016763)	1/39	0.3544869840724297	0.4752292755905498	0	0	2.3398530109056423	2.426623300970964	UPP1
Phosphotyrosine Residue Binding (GO:0001784)	1/39	0.3544869840724297	0.4752292755905498	0	0	2.3398530109056423	2.426623300970964	SAMSN1
Phosphatidylinositol-3-Phosphate Binding (GO:0032266)	1/40	0.3616985043748635	0.4827888732307961	0	0	2.27974127974128	2.318369842960962	NCF4
RNA Endonuclease Activity (GO:0004521)	1/41	0.36882981633779843	0.48806359317113845	0	0	2.222635135135135	2.216900611273689	NYNRIN
Neutral L-amino Acid Transmembrane Transporter Activity (GO:0015175)	1/41	0.36882981633779843	0.48806359317113845	0	0	2.222635135135135	2.216900611273689	SLC36A2
Lipase Activity (GO:0016298)	1/42	0.3758818080883837	0.4910455960984417	0	0	2.1683146561195343	2.1216536635142433	DAGLB
Promoter-Specific Chromatin Binding (GO:1990841)	1/42	0.3758818080883837	0.4910455960984417	0	0	2.1683146561195343	2.1216536635142433	KLF4
Regulatory RNA Binding (GO:0061980)	1/42	0.3758818080883837	0.4910455960984417	0	0	2.1683146561195343	2.1216536635142433	TLR9
ATP Binding (GO:0005524)	4/279	0.3778770719053445	0.4915604282836473	0	0	1.2952760481527605	1.260544960287261	PDK2;SYN1;ABCG1;TGFBR1
Single-Stranded RNA Binding (GO:0003727)	1/43	0.3828553580133	0.4959349996206038	0	0	2.1165808665808665	2.0321250916581413	JMJD6
Protein Kinase Inhibitor Activity (GO:0004860)	1/45	0.39657059722794424	0.5094023989497025	0	0	2.020167895167895	1.8684557159778892	CDKN1B
Protein Phosphorylated Amino Acid Binding (GO:0045309)	1/45	0.39657059722794424	0.5094023989497025	0	0	2.020167895167895	1.8684557159778892	SAMSN1
Metallopeptidase Activity (GO:0008237)	2/124	0.4032908264833488	0.5137651308678389	0	0	1.4579778948149247	1.3239858239999787	ADAM22;MMP8
Cyclin-Dependent Protein Serine/Threonine Kinase Regulator Activity (GO:0016538)	1/46	0.40331399524152833	0.5137651308678389	0	0	1.9751751751751752	1.793537820929153	CDKN1B
Serine-Type Endopeptidase Activity (GO:0004252)	2/125	0.4071866195951055	0.5158384724049467	0	0	1.4460508405989037	1.2992530718007933	HP;MMP8
Voltage-Gated Calcium Channel Activity (GO:0005245)	1/47	0.40998236894725415	0.5158384724049467	0	0	1.9321386603995299	1.7227742845177336	SCN3A
Calcium-Dependent Phospholipid Binding (GO:0005544)	1/47	0.40998236894725415	0.5158384724049467	0	0	1.9321386603995299	1.7227742845177336	ESYT1
Purine Ribonucleoside Triphosphate Binding (GO:0035639)	6/476	0.438730893052054	0.5496513559050124	0	0	1.135817236984018	0.9357646722665496	DIRAS2;PDK2;SYN1;ABCG1;TGFBR1;RND1
Phosphoric Ester Hydrolase Activity (GO:0042578)	1/52	0.44222763813856036	0.5496513559050124	0	0	1.742271683448154	1.4215726250949334	DUSP5
Exopeptidase Activity (GO:0008238)	1/52	0.44222763813856036	0.5496513559050124	0	0	1.742271683448154	1.4215726250949334	DPEP2
Antiporter Activity (GO:0015297)	1/53	0.44846299912994003	0.5551537932777886	0	0	1.7086798336798337	1.3702400812783297	SLC25A15
Flavin Adenine Dinucleotide Binding (GO:0050660)	1/55	0.4607263007266927	0.5680440735867255	0	0	1.6452285618952285	1.2749717167804946	SQLE
G Protein-Coupled Receptor Binding (GO:0001664)	2/140	0.4640457975145393	0.5698482393478542	0	0	1.2878877303429732	0.9888041772490519	CALCB;FPR1
Hydrolase Activity, Acting On Carbon-Nitrogen (But Not Peptide) Bonds, In Linear Amides (GO:0016811)	1/56	0.46675577065007995	0.5707707663432698	0	0	1.6152334152334151	1.230725700597458	NAAA
RNA Polymerase II-specific DNA-binding Transcription Factor Binding (GO:0061629)	3/228	0.46851541732411733	0.5707707663432698	0	0	1.184969696969697	0.8984277546118168	NFKBIA;TACC1;KLF4
Serine-Type Peptidase Activity (GO:0008236)	2/142	0.4713862041301147	0.5719982793199416	0	0	1.2693600517129928	0.9546572036607516	HP;MMP8
Cadherin Binding (GO:0045296)	4/319	0.47719362795072845	0.5762138488532514	0	0	1.128477205189534	0.8348846105177431	EHD4;GPRC5A;PROM1;S100A11
Endonuclease Activity (GO:0004519)	1/58	0.47861410898234247	0.5762138488532514	0	0	1.5584005057689267	1.1483239695072995	NYNRIN
Secondary Active Transmembrane Transporter Activity (GO:0015291)	1/60	0.49020989592250014	0.5878688986258107	0	0	1.5054206749122003	1.0732469472002322	SLC25A15
Microtubule Binding (GO:0008017)	3/239	0.4996234275591091	0.5968043339389929	0	0	1.129102465331279	0.7834848885401298	EML6;TRPV4;MTUS1
PDZ Domain Binding (GO:0030165)	1/62	0.501548919075766	0.5968043339389929	0	0	1.4559149313247675	1.0046601124866872	ATP2B1
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific (GO:0001227)	3/243	0.510707851909795	0.605305805698097	0	0	1.1100568181818182	0.7459110828265214	NFIL3;NACC2;GLIS3
Acyltransferase Activity, Transferring Groups Other Than Amino-Acyl Groups (GO:0016747)	1/64	0.5126368387019714	0.605305805698097	0	0	1.4095524095524095	0.9418454433933715	PLA2G15
Double-Stranded RNA Binding (GO:0003725)	1/65	0.5180883695338917	0.6093989633981025	0	0	1.3874577702702702	0.9124053463628209	RFTN1
GDP Binding (GO:0019003)	1/67	0.528809976254315	0.6196361172140257	0	0	1.3452770952770954	0.8571111824774879	DIRAS2
ATPase Binding (GO:0051117)	1/73	0.559570690958327	0.6531870803201765	0	0	1.2327952952952952	0.7157429651056952	BBC3
GTPase Activity (GO:0003924)	3/265	0.5692520074327612	0.6619710844009761	0	0	1.0157009021512837	0.5722784390407244	RGS2;DIRAS2;RND1
Protein Tyrosine Phosphatase Activity (GO:0004725)	1/76	0.5741928516097557	0.6651970016762075	0	0	1.1833033033033034	0.6564847931079776	DUSP5
Ribonucleoside Triphosphate Phosphatase Activity (GO:0017111)	3/270	0.5819475018510939	0.6716461769484429	0	0	0.9964249233912156	0.5394395810881356	RGS2;DIRAS2;RND1
Ubiquitin Protein Ligase Binding (GO:0031625)	3/271	0.5844582350157367	0.6720175211604162	0	0	0.9926560379918589	0.5331257334864635	NFKBIA;CDKN1B;TPI1
Actin Binding (GO:0003779)	2/183	0.6076392661693182	0.6960643832611219	0	0	0.9797755056123597	0.4880985703691732	TRPV4;SYNE2
mRNA Binding (GO:0003729)	3/282	0.6114400015664602	0.6978144255795661	0	0	0.9529814271749756	0.4688082018610953	NYNRIN;SLPI;ZFP36L1
Heme Binding (GO:0020037)	1/87	0.6237914499040415	0.7092739819279287	0	0	1.0313743976534675	0.48674598891695187	NRG1
Ubiquitin-Like Protein Ligase Binding (GO:0044389)	3/289	0.6279924397902927	0.7114157897255345	0	0	0.9293229497774952	0.4323462684111166	NFKBIA;CDKN1B;TPI1
Calcium Channel Activity (GO:0005262)	1/91	0.6403638510110135	0.7227636112514012	0	0	0.9853353353353353	0.4391824310093467	TRPV4
mRNA 3'-UTR Binding (GO:0003730)	1/93	0.6483754443777564	0.7291254997215063	0	0	0.9638170779475127	0.41760783049794187	ZFP36L1
GTP Binding (GO:0005525)	2/201	0.6584923512486542	0.736867976938677	0	0	0.8903340230564588	0.3719836678468096	DIRAS2;RND1
Single-Stranded DNA Binding (GO:0003697)	1/96	0.6600608913945804	0.736867976938677	0	0	0.9332385016595542	0.3876889140170382	NABP1
Transcription Coregulator Binding (GO:0001221)	1/99	0.6713596806547701	0.7440701153827236	0	0	0.9045320831035116	0.36041103363571086	TRERF1
Histone Deacetylase Binding (GO:0042826)	1/99	0.6713596806547701	0.7440701153827236	0	0	0.9045320831035116	0.36041103363571086	NACC2
Ubiquitin Protein Ligase Activity (GO:0061630)	3/311	0.6768190270214833	0.7474224507035805	0	0	0.8619687131050767	0.3364706576053684	ZNRF2;MARCHF8;RNF150
GTPase Activator Activity (GO:0005096)	2/211	0.6843999684866872	0.7530852699835591	0	0	0.8473013055056399	0.3213074861081793	RGS2;ARAP3
Monoatomic Cation Channel Activity (GO:0005261)	1/105	0.6928478214327627	0.7575191447116096	0	0	0.8520876645876646	0.31266922099758554	TRPV4
Ubiquitin-Like Protein Ligase Activity (GO:0061659)	3/319	0.6933644288728414	0.7575191447116096	0	0	0.8398014959723821	0.30753492707987773	ZNRF2;MARCHF8;RNF150
Kinase Activity (GO:0016301)	1/106	0.6962906274270954	0.7580185199294974	0	0	0.843929643929644	0.3054925201243984	CAMK2A
Tubulin Binding (GO:0015631)	3/322	0.6994030686303432	0.7587164030724923	0	0	0.8317754345967512	0.2973830631798072	EML6;TRPV4;MTUS1
Transcription Regulatory Region Nucleic Acid Binding (GO:0001067)	2/224	0.7156582003390142	0.7714376167644866	0	0	0.7971546206840324	0.26669015081541986	JUND;KLF4
Phosphatase Binding (GO:0019902)	1/112	0.7161554422732205	0.7714376167644866	0	0	0.7980683386088792	0.2664415292685101	CDKN1B
Guanyl Ribonucleotide Binding (GO:0032561)	2/226	0.7202305798834909	0.7731146434413696	0	0	0.7899563671622495	0.25925093644479913	DIRAS2;RND1
Endopeptidase Activity (GO:0004175)	3/335	0.7245332857271786	0.7734665377376833	0	0	0.7986719605695509	0.2573541292697508	ADAM22;HP;MMP8
Protein Phosphatase Binding (GO:0019903)	1/115	0.7255972731871425	0.7734665377376833	0	0	0.7769480006322111	0.24921394805651703	CDKN1B
Calcium Ion Binding (GO:0005509)	3/346	0.7444984847637707	0.7908686326037287	0	0	0.7726212562947257	0.22795762297066638	PLSCR1;IDS;ESYT1
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific (GO:0001228)	3/348	0.7480026740035416	0.7918511066175423	0	0	0.7680632411067194	0.2230061836526035	PLSCR1;GLIS3;KLF4
Kinase Binding (GO:0019900)	4/460	0.7574916445218217	0.7991406696501693	0	0	0.7738924937915566	0.21494304645076576	CDKN1B;RGCC;TRPV4;SYN1
Sequence-Specific DNA Binding (GO:0043565)	6/717	0.8147890670125505	0.8566446697700446	0	0	0.7414493768107489	0.15186811948646511	JUND;NFIX;TEF;TLR9;KLF4;PKNOX2
Protein Kinase Binding (GO:0019901)	4/511	0.8248532669199868	0.858876836271198	0	0	0.6942080282438554	0.13366959391080468	CDKN1B;RGCC;TRPV4;SYN1
DNA-binding Transcription Factor Binding (GO:0140297)	2/282	0.8250657571032235	0.858876836271198	0	0	0.6301551389786684	0.12117391186779103	NAAA;KLF4
Magnesium Ion Binding (GO:0000287)	1/155	0.8253051032573401	0.858876836271198	0	0	0.573973323973324	0.1102041058656365	PLSCR1
Metal Ion Binding (GO:0046872)	4/521	0.8360812228350563	0.8671518088187914	0	0	0.6804271216978882	0.12181653698862135	PLSCR1;IDS;NRG1;ESYT1
Ubiquitin-Protein Transferase Activity (GO:0004842)	3/412	0.8411060947786531	0.8694261653099209	0	0	0.6457434985552345	0.111737823738729	ZNRF2;MARCHF8;RNF150
Double-Stranded DNA Binding (GO:0003690)	5/650	0.8542475242443491	0.8800469461175007	0	0	0.6803214565109167	0.10717395500657978	JUND;NFIX;TEF;KLF4;PKNOX2
Cis-Regulatory Region Sequence-Specific DNA Binding (GO:0000987)	9/1098	0.8688002267550503	0.8920457177719078	0	0	0.7217115934193249	0.10150301157869616	JUND;NFIX;NFIL3;TEF;NACC2;GLIS3;KLF4;PKNOX2;MXD4
Protein Heterodimerization Activity (GO:0046982)	1/190	0.8824127982465021	0.901683300363145	0	0	0.46684780018113353	0.058400468999002954	ABCG1
RNA Polymerase II Cis-Regulatory Region Sequence-Specific DNA Binding (GO:0000978)	9/1122	0.884060825437481	0.901683300363145	0	0	0.7052422097387712	0.0869065825808157	JUND;NFIX;NFIL3;TEF;NACC2;GLIS3;KLF4;PKNOX2;MXD4
Transcription Cis-Regulatory Region Binding (GO:0000976)	3/474	0.9014422492562866	0.9161167789650841	0	0	0.5589461493920093	0.05799586070443521	JUND;NFIL3;KLF4
Sequence-Specific Double-Stranded DNA Binding (GO:1990837)	5/715	0.9041804039948551	0.9161167789650841	0	0	0.6159387517767153	0.06204127864848597	JUND;NFIX;TEF;KLF4;PKNOX2
Ubiquitin-Like Protein Transferase Activity (GO:0019787)	1/240	0.9332837432029575	0.9400854456080158	0	0	0.36823853141844776	0.025425399548186546	MARCHF8
RNA Polymerase II Transcription Regulatory Region Sequence-Specific DNA Binding (GO:0000977)	9/1225	0.933961110457475	0.9400854456080158	0	0	0.6419430951795376	0.04385785991132289	JUND;NFIX;NFIL3;TEF;NACC2;GLIS3;KLF4;PKNOX2;MXD4
RNA Binding (GO:0003723)	7/1411	0.9963687525523106	0.9993202983849732	0	0	0.42408924237627943	0.001542775777606871	NYNRIN;SLPI;RFTN1;SAMSN1;TNS1;JMJD6;ZFP36L1
DNA Binding (GO:0003677)	2/846	0.9993202983849732	0.9993202983849732	0	0	0.20300872809933307	1.3803227605012352E-4	SLPI;NABP1
